Manufactured Solutions for Verification of a Coupled Flow and Material Response Code

Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/106457/1/AIAA2013-2646.pd

Quantum repeaters and quantum key distribution: analysis of secret key rates

We analyze various prominent quantum repeater protocols in the context of long-distance quantum key distribution. These protocols are the original quantum repeater proposal by Briegel, D\"ur, Cirac and Zoller, the so-called hybrid quantum repeater using optical coherent states dispersively interacting with atomic spin qubits, and the Duan-Lukin-Cirac-Zoller-type repeater using atomic ensembles together with linear optics and, in its most recent extension, heralded qubit amplifiers. For our analysis, we investigate the most important experimental parameters of every repeater component and find their minimally required values for obtaining a nonzero secret key. Additionally, we examine in detail the impact of device imperfections on the final secret key rate and on the optimal number of rounds of distillation when the entangled states are purified right after their initial distribution.Comment: Published versio

Thrust at N^3LL with Power Corrections and a Precision Global Fit for alphas(mZ)

We give a factorization formula for the e+e- thrust distribution dsigma/dtau with tau=1-T based on soft-collinear effective theory. The result is applicable for all tau, i.e. in the peak, tail, and far-tail regions. The formula includes O(alphas^3) fixed-order QCD results, resummation of singular partonic alphas^j ln^k(tau)/tau terms with N^3LL accuracy, hadronization effects from fitting a universal nonperturbative soft function defined in field theory, bottom quark mass effects, QED corrections, and the dominant top mass dependent terms from the axial anomaly. We do not rely on Monte Carlo generators to determine nonperturbative effects since they are not compatible with higher order perturbative analyses. Instead our treatment is based on fitting nonperturbative matrix elements in field theory, which are moments Omega_i of a nonperturbative soft function. We present a global analysis of all available thrust data measured at center-of-mass energies Q=35 to 207 GeV in the tail region, where a two parameter fit to $\alpha_s(m_Z)$ and the first moment Omega_1 suffices. We use a short distance scheme to define Omega_1, called the R-gap scheme, thus ensuring that the perturbative dsigma/dtau does not suffer from an O(Lambda_QCD) renormalon ambiguity. We find alphas(mZ)=0.1135 \pm (0.0002)_{expt} \pm (0.0005)_{hadr} \pm (0.0009)_{pert}, with chi^2/dof=0.91, where the displayed 1-sigma errors are the total experimental error, the hadronization uncertainty, and the perturbative theory uncertainty, respectively. The hadronization uncertainty in alphas is significantly decreased compared to earlier analyses by our two parameter fit, which determines Omega_1=0.323 GeV with 16% uncertainty.Comment: 45 pages, 21 figures, v2: added discussion of bin integration vs. cumulant differences; comparison to Becher & Schwartz improved; typo in Eq.55 fixe

A field-theoretic approach to the Wiener Sausage

The Wiener Sausage, the volume traced out by a sphere attached to a Brownian particle, is a classical problem in statistics and mathematical physics. Initially motivated by a range of field-theoretic, technical questions, we present a single loop renormalised perturbation theory of a stochastic process closely related to the Wiener Sausage, which, however, proves to be exact for the exponents and some amplitudes. The field-theoretic approach is particularly elegant and very enjoyable to see at work on such a classic problem. While we recover a number of known, classical results, the field-theoretic techniques deployed provide a particularly versatile framework, which allows easy calculation with different boundary conditions even of higher momenta and more complicated correlation functions. At the same time, we provide a highly instructive, non-trivial example for some of the technical particularities of the field-theoretic description of stochastic processes, such as excluded volume, lack of translational invariance and immobile particles. The aim of the present work is not to improve upon the well-established results for the Wiener Sausage, but to provide a field-theoretic approach to it, in order to gain a better understanding of the field-theoretic obstacles to overcome.Comment: 45 pages, 3 Figures, Springer styl

Emergent Properties of Tumor Microenvironment in a Real-life Model of Multicell Tumor Spheroids

Multicellular tumor spheroids are an important {\it in vitro} model of the pre-vascular phase of solid tumors, for sizes well below the diagnostic limit: therefore a biophysical model of spheroids has the ability to shed light on the internal workings and organization of tumors at a critical phase of their development. To this end, we have developed a computer program that integrates the behavior of individual cells and their interactions with other cells and the surrounding environment. It is based on a quantitative description of metabolism, growth, proliferation and death of single tumor cells, and on equations that model biochemical and mechanical cell-cell and cell-environment interactions. The program reproduces existing experimental data on spheroids, and yields unique views of their microenvironment. Simulations show complex internal flows and motions of nutrients, metabolites and cells, that are otherwise unobservable with current experimental techniques, and give novel clues on tumor development and strong hints for future therapies.Comment: 20 pages, 10 figures. Accepted for publication in PLOS One. The published version contains links to a supplementary text and three video file

All stationary axi-symmetric local solutions of topologically massive gravity

We classify all stationary axi-symmetric solutions of topologically massive gravity into Einstein, Schr\"odinger, warped and generic solutions. We construct explicitly all local solutions in the first three sectors and present an algorithm for the numerical construction of all local solutions in the generic sector. The only input for this algorithm is the value of one constant of motion if the solution has an analytic centre, and three constants of motion otherwise. We present several examples, including soliton solutions that asymptote to warped AdS.Comment: 42 pages, 9 figures. v2: Changed potentially confusing labelling of one sector, added references. v3: Minor changes, matches published versio

Theory and Computation of the Spheroidal Wave Functions

In this paper we report on a package, written in the Mathematica computer algebra system, which has been developed to compute the spheroidal wave functions of Meixner [J. Meixner and R.W. Schaefke, Mathieusche Funktionen und Sphaeroidfunktionen, 1954] and is available online (www.physics.uwa.edu.au/~falloon/spheroidal/spheroidal.html). This package represents a substantial contribution to the existing software, since it computes the spheroidal wave functions to arbitrary precision for general complex parameters mu, nu, gamma and argument z; existing software can only handle integer mu, nu and does not give arbitrary precision. The package also incorporates various special cases and computes analytic power series and asymptotic expansions in the parameter gamma. The spheroidal wave functions of Flammer [C. Flammer, Spheroidal Wave Functions, 1957] are included as a special case of Meixner's more general functions. This paper presents a concise review of the general theory of spheroidal wave functions and a description of the formulas and algorithms used in their computation, and gives high-precision numerical examples.Comment: 26 pages, 4 Appendices, 5 Table

Quantum fluctuations of one-dimensional free fermions and Fisher-Hartwig formula for Toeplitz determinants

We revisit the problem of finding the probability distribution of a fermionic number of one-dimensional spinless free fermions on a segment of a given length. The generating function for this probability distribution can be expressed as a determinant of a Toeplitz matrix. We use the recently proven generalized Fisher--Hartwig conjecture on the asymptotic behavior of such determinants to find the generating function for the full counting statistics of fermions on a line segment. Unlike the method of bosonization, the Fisher--Hartwig formula correctly takes into account the discreteness of charge. Furthermore, we check numerically the precision of the generalized Fisher--Hartwig formula, find that it has a higher precision than rigorously proven so far, and conjecture the form of the next-order correction to the existing formula.Comment: 17 pages, 2 figures, Latex, iopart.cl

An assessment of existing models for individualized breast cancer risk estimation in a screening program in Spain

Background: The aim of this study was to evaluate the calibration and discriminatory power of three predictive models of breast cancer risk. Methods: We included 13,760 women who were first-time participants in the Sabadell-Cerdanyola Breast Cancer Screening Program, in Catalonia, Spain. Projections of risk were obtained at three and five years for invasive cancer using the Gail, Chen and Barlow models. Incidence and mortality data were obtained from the Catalan registries. The calibration and discrimination of the models were assessed using the Hosmer-Lemeshow C statistic, the area under the receiver operating characteristic curve (AUC) and the Harrell’s C statistic. Results: The Gail and Chen models showed good calibration while the Barlow model overestimated the number of cases: the ratio between estimated and observed values at 5 years ranged from 0.86 to 1.55 for the first two models and from 1.82 to 3.44 for the Barlow model. The 5-year projection for the Chen and Barlow models had the highest discrimination, with an AUC around 0.58. The Harrell’s C statistic showed very similar values in the 5-year projection for each of the models. Although they passed the calibration test, the Gail and Chen models overestimated the number of cases in some breast density categories. Conclusions: These models cannot be used as a measure of individual risk in early detection programs to customize screening strategies. The inclusion of longitudinal measures of breast density or other risk factors in joint models of survival and longitudinal data may be a step towards personalized early detection of BC.This study was funded by grant PS09/01340 and The Spanish Network on Chronic Diseases REDISSEC (RD12/0001/0007) from the Health Research Fund (Fondo de Investigación Sanitaria) of the Spanish Ministry of Health